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Antitumor activity of irinotecan with ellagic acid in C6 glioma cells

OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, with irinotecan, an inhibitor of topoisomerase I enzyme, on the growth, cadher...

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Detalles Bibliográficos
Autores principales: Cetin, Abdurrahman, Biltekin, Burcu, Ozevren, Huseyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Médica Brasileira 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574968/
https://www.ncbi.nlm.nih.gov/pubmed/35946772
http://dx.doi.org/10.1590/1806-9282.20220130