Cargando…
Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting
OBJECTIVE: This study aims to examine the predictive role of systemic immune-inflammation index on postoperative new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting. METHODS: A total of 722 patients undergoing elective off-pump coronary artery bypass graftin...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Médica Brasileira
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575030/ https://www.ncbi.nlm.nih.gov/pubmed/36228255 http://dx.doi.org/10.1590/1806-9282.20220295 |
_version_ | 1784811234108899328 |
---|---|
author | Topal, Dursun Korkmaz, Ufuk Turan Kursat Velioglu, Yusuf Yuksel, Ahmet Donmez, Ibrahim Uçaroğlu, Erhan Renan Kayis, Seyit Ali |
author_facet | Topal, Dursun Korkmaz, Ufuk Turan Kursat Velioglu, Yusuf Yuksel, Ahmet Donmez, Ibrahim Uçaroğlu, Erhan Renan Kayis, Seyit Ali |
author_sort | Topal, Dursun |
collection | PubMed |
description | OBJECTIVE: This study aims to examine the predictive role of systemic immune-inflammation index on postoperative new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting. METHODS: A total of 722 patients undergoing elective off-pump coronary artery bypass grafting between January 2017 and September 2021 were included in this study and divided into two groups as the atrial fibrillation group (n=172) and the non-atrial fibrillation group (n=550). Both groups were compared in terms of patients’ baseline clinical features, operative and postoperative variables, and preoperative hematological indices derived from the complete blood count analysis. Multivariate logistic regression and receiver-operating characteristic curve analyses were performed to detect the independent predictors of postoperative new-onset atrial fibrillation. RESULTS: The median age and length of hospital stay in the atrial fibrillation group were significantly higher than those in the non-atrial fibrillation group. The median values of white blood cell, platelet, neutrophil, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and systemic immune-inflammation in the atrial fibrillation group were significantly greater than in those in the non- atrial fibrillation group. Logistic regression analysis demonstrated that age, platelet, platelet/lymphocyte ratio, and systemic immune-inflammation were independent predictors of postoperative new-onset atrial fibrillation. receiver-operating characteristic curve analysis revealed that systemic immune-inflammation of 706.7×10(3)/mm(3) constituted cut-off value to predict the occurrence of new-onset atrial fibrillation with 86.6% sensitivity and 29.3% specificity. CONCLUSION: Our study revealed for the first time that systemic immune-inflammation predicted new-onset atrial fibrillation after off-pump coronary artery bypass grafting. |
format | Online Article Text |
id | pubmed-9575030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Associação Médica Brasileira |
record_format | MEDLINE/PubMed |
spelling | pubmed-95750302022-10-19 Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting Topal, Dursun Korkmaz, Ufuk Turan Kursat Velioglu, Yusuf Yuksel, Ahmet Donmez, Ibrahim Uçaroğlu, Erhan Renan Kayis, Seyit Ali Rev Assoc Med Bras (1992) Original Article OBJECTIVE: This study aims to examine the predictive role of systemic immune-inflammation index on postoperative new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting. METHODS: A total of 722 patients undergoing elective off-pump coronary artery bypass grafting between January 2017 and September 2021 were included in this study and divided into two groups as the atrial fibrillation group (n=172) and the non-atrial fibrillation group (n=550). Both groups were compared in terms of patients’ baseline clinical features, operative and postoperative variables, and preoperative hematological indices derived from the complete blood count analysis. Multivariate logistic regression and receiver-operating characteristic curve analyses were performed to detect the independent predictors of postoperative new-onset atrial fibrillation. RESULTS: The median age and length of hospital stay in the atrial fibrillation group were significantly higher than those in the non-atrial fibrillation group. The median values of white blood cell, platelet, neutrophil, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and systemic immune-inflammation in the atrial fibrillation group were significantly greater than in those in the non- atrial fibrillation group. Logistic regression analysis demonstrated that age, platelet, platelet/lymphocyte ratio, and systemic immune-inflammation were independent predictors of postoperative new-onset atrial fibrillation. receiver-operating characteristic curve analysis revealed that systemic immune-inflammation of 706.7×10(3)/mm(3) constituted cut-off value to predict the occurrence of new-onset atrial fibrillation with 86.6% sensitivity and 29.3% specificity. CONCLUSION: Our study revealed for the first time that systemic immune-inflammation predicted new-onset atrial fibrillation after off-pump coronary artery bypass grafting. Associação Médica Brasileira 2022-10-07 /pmc/articles/PMC9575030/ /pubmed/36228255 http://dx.doi.org/10.1590/1806-9282.20220295 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Topal, Dursun Korkmaz, Ufuk Turan Kursat Velioglu, Yusuf Yuksel, Ahmet Donmez, Ibrahim Uçaroğlu, Erhan Renan Kayis, Seyit Ali Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title | Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title_full | Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title_fullStr | Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title_full_unstemmed | Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title_short | Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
title_sort | systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575030/ https://www.ncbi.nlm.nih.gov/pubmed/36228255 http://dx.doi.org/10.1590/1806-9282.20220295 |
work_keys_str_mv | AT topaldursun systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT korkmazufukturankursat systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT veliogluyusuf systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT yukselahmet systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT donmezibrahim systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT ucarogluerhanrenan systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting AT kayisseyitali systemicimmuneinflammationindexasanovelpredictorofatrialfibrillationafteroffpumpcoronaryarterybypassgrafting |