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Intestine-derived α-synuclein initiates and aggravates pathogenesis of Parkinson’s disease in Drosophila

BACKGROUND: Aberrant aggregation of α-synuclein (α-syn) is a key pathological feature of Parkinson’s disease (PD), but the precise role of intestinal α-syn in the progression of PD is unclear. In a number of genetic Drosophila models of PD, α-syn was frequently ectopically expressed in the neural sy...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Lim, Kah-Leong, Tan, Eng-King
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575256/ https://www.ncbi.nlm.nih.gov/pubmed/36253844 http://dx.doi.org/10.1186/s40035-022-00318-w

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