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Icariin alleviates osteoarthritis through PI3K/Akt/mTOR/ULK1 signaling pathway

OBJECTIVES: This study aims to investigate the effects of Icariin (ICA) on interleukin-1β (IL-1β)-induced osteoarthritis (OA) and its potential mechanism of action. METHODS: SW1353 chondrocytes were pretreated with ICA for 2 h, followed by stimulation with IL-1β to mimic OA. Expression levels of mat...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Pan, Xiaoli, Zhao, Jing, Li, Chunyan, Lin, Yupei, Wang, Yu, Liu, Xu, Tian, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575285/
https://www.ncbi.nlm.nih.gov/pubmed/36253872
http://dx.doi.org/10.1186/s40001-022-00820-x