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Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target
BACKGROUND: Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and explore potential pathogenic targets. METHODS: In the present study, strychnin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575290/ https://www.ncbi.nlm.nih.gov/pubmed/36244968 http://dx.doi.org/10.1186/s12906-022-03753-4 |