Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing

Hepatoid adenocarcinoma (HAC) is a rare malignancy that may mimic hepatocellular carcinoma (HCC) given its hepatoid histologic appearance and production of alpha fetoprotein. Clinical management and prognosis of HAC varies considerably from HCC. We present two cases of metastatic HAC in a cirrhotic...

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Detalles Bibliográficos
Autores principales: Nguyen, Paul, Hui, Samuel, Robertson, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575327/
https://www.ncbi.nlm.nih.gov/pubmed/36262535
http://dx.doi.org/10.1002/jgh3.12813
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author Nguyen, Paul
Hui, Samuel
Robertson, Marcus
author_facet Nguyen, Paul
Hui, Samuel
Robertson, Marcus
author_sort Nguyen, Paul
collection PubMed
description Hepatoid adenocarcinoma (HAC) is a rare malignancy that may mimic hepatocellular carcinoma (HCC) given its hepatoid histologic appearance and production of alpha fetoprotein. Clinical management and prognosis of HAC varies considerably from HCC. We present two cases of metastatic HAC in a cirrhotic liver diagnosed after biopsy and histopathological evaluation. The cases underscore the importance of recognizing the limitations of diagnostic imaging and pursuing a biopsy where there is diagnostic uncertainty.
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spelling pubmed-95753272022-10-18 Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing Nguyen, Paul Hui, Samuel Robertson, Marcus JGH Open Case Reports Hepatoid adenocarcinoma (HAC) is a rare malignancy that may mimic hepatocellular carcinoma (HCC) given its hepatoid histologic appearance and production of alpha fetoprotein. Clinical management and prognosis of HAC varies considerably from HCC. We present two cases of metastatic HAC in a cirrhotic liver diagnosed after biopsy and histopathological evaluation. The cases underscore the importance of recognizing the limitations of diagnostic imaging and pursuing a biopsy where there is diagnostic uncertainty. Wiley Publishing Asia Pty Ltd 2022-09-08 /pmc/articles/PMC9575327/ /pubmed/36262535 http://dx.doi.org/10.1002/jgh3.12813 Text en © 2022 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Nguyen, Paul
Hui, Samuel
Robertson, Marcus
Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title_full Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title_fullStr Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title_full_unstemmed Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title_short Hepatoid adenocarcinoma: A wolf in hepatocellular carcinoma's clothing
title_sort hepatoid adenocarcinoma: a wolf in hepatocellular carcinoma's clothing
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575327/
https://www.ncbi.nlm.nih.gov/pubmed/36262535
http://dx.doi.org/10.1002/jgh3.12813
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AT huisamuel hepatoidadenocarcinomaawolfinhepatocellularcarcinomasclothing
AT robertsonmarcus hepatoidadenocarcinomaawolfinhepatocellularcarcinomasclothing

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