Cargando…

Silent progressive bilateral papillitis after COVID-19 vaccination: A case report

We report the case of a patient who developed asymptomatic bilateral papillitis after coronavirus disease 2019 (COVID-19) vaccination. PATIENT CONCERNS: A 61-year-old man presented to our tertiary clinic with bilateral optic disc edema, which was incidentally detected during his visit to a primary o...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Geun Woo, Park, Hyeong Seok, Lee, Donghun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575402/
https://www.ncbi.nlm.nih.gov/pubmed/36254071
http://dx.doi.org/10.1097/MD.0000000000031112
_version_ 1784811311814672384
author Lee, Geun Woo
Park, Hyeong Seok
Lee, Donghun
author_facet Lee, Geun Woo
Park, Hyeong Seok
Lee, Donghun
author_sort Lee, Geun Woo
collection PubMed
description We report the case of a patient who developed asymptomatic bilateral papillitis after coronavirus disease 2019 (COVID-19) vaccination. PATIENT CONCERNS: A 61-year-old man presented to our tertiary clinic with bilateral optic disc edema, which was incidentally detected during his visit to a primary ophthalmology clinic. He had received an adenovirus-vectored COVID-19 vaccine 2 weeks before the optic disc edema was detected and had experienced no ocular discomfort, except for a floater in his right eye. Although his visual acuity was normal and he had no color vision deficiencies or marked visual field defects, the optic disc edema worsened over several days. Orbital magnetic resonance imaging showed no optic tract enhancement, and lumbar puncture revealed normal cerebrospinal fluid pressure. The patient tested negative for aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies and Leber hereditary optic neuropathy-associated gene mutations. DIAGNOSIS: The patient was diagnosed with bilateral papillitis, possibly induced by the COVID-19 vaccination. INTERVENTIONS: The patient received steroid pulse therapy with methylprednisolone (500 mg/day) for 3 days followed by an oral prednisolone taper for 3 weeks. OUTCOMES: The patient’s papillitis started to subside 3 weeks after he received systemic steroid therapy and completely resolved without any sequelae 2 months later. A year after the diagnosis, the fundus remained stable without disease recurrence or optic disc atrophy. LESSONS: Healthy individuals receiving COVID-19 vaccines may present with various manifestations of optic neuritis. In the present case, the patient presented with asymptomatic progressive bilateral optic disc edema and had a favorable long-term course after receiving steroid therapy.
format Online
Article
Text
id pubmed-9575402
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-95754022022-10-17 Silent progressive bilateral papillitis after COVID-19 vaccination: A case report Lee, Geun Woo Park, Hyeong Seok Lee, Donghun Medicine (Baltimore) 5800 We report the case of a patient who developed asymptomatic bilateral papillitis after coronavirus disease 2019 (COVID-19) vaccination. PATIENT CONCERNS: A 61-year-old man presented to our tertiary clinic with bilateral optic disc edema, which was incidentally detected during his visit to a primary ophthalmology clinic. He had received an adenovirus-vectored COVID-19 vaccine 2 weeks before the optic disc edema was detected and had experienced no ocular discomfort, except for a floater in his right eye. Although his visual acuity was normal and he had no color vision deficiencies or marked visual field defects, the optic disc edema worsened over several days. Orbital magnetic resonance imaging showed no optic tract enhancement, and lumbar puncture revealed normal cerebrospinal fluid pressure. The patient tested negative for aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies and Leber hereditary optic neuropathy-associated gene mutations. DIAGNOSIS: The patient was diagnosed with bilateral papillitis, possibly induced by the COVID-19 vaccination. INTERVENTIONS: The patient received steroid pulse therapy with methylprednisolone (500 mg/day) for 3 days followed by an oral prednisolone taper for 3 weeks. OUTCOMES: The patient’s papillitis started to subside 3 weeks after he received systemic steroid therapy and completely resolved without any sequelae 2 months later. A year after the diagnosis, the fundus remained stable without disease recurrence or optic disc atrophy. LESSONS: Healthy individuals receiving COVID-19 vaccines may present with various manifestations of optic neuritis. In the present case, the patient presented with asymptomatic progressive bilateral optic disc edema and had a favorable long-term course after receiving steroid therapy. Lippincott Williams & Wilkins 2022-10-14 /pmc/articles/PMC9575402/ /pubmed/36254071 http://dx.doi.org/10.1097/MD.0000000000031112 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5800
Lee, Geun Woo
Park, Hyeong Seok
Lee, Donghun
Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title_full Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title_fullStr Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title_full_unstemmed Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title_short Silent progressive bilateral papillitis after COVID-19 vaccination: A case report
title_sort silent progressive bilateral papillitis after covid-19 vaccination: a case report
topic 5800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575402/
https://www.ncbi.nlm.nih.gov/pubmed/36254071
http://dx.doi.org/10.1097/MD.0000000000031112
work_keys_str_mv AT leegeunwoo silentprogressivebilateralpapillitisaftercovid19vaccinationacasereport
AT parkhyeongseok silentprogressivebilateralpapillitisaftercovid19vaccinationacasereport
AT leedonghun silentprogressivebilateralpapillitisaftercovid19vaccinationacasereport