Recurrent vincristine‐associated fever in a child with Wilms tumor

BACKGROUND: Fever is a common complaint among children with an underlying oncologic diagnosis, especially during chemotherapy courses and periods of neutropenia. Chemotherapy‐induced fever is well described in relation to specific chemotherapy agents. However, fever induced by vincristine (VCR) has only been rarely reported. CASE: We describe a case of a 5‐year‐old female with stage III Wilms tumor who had recurrent VCR‐associated fever that was controlled with prophylactic dexamethasone and acetaminophen. CONCLUSION: In patients developing recurrent fever following chemotherapy with VCR, febrile allergic reaction and prophylactic treatment should be considered after exhaustion of appropriate investigations.