Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus

The biosynthesis of host lipids and/or lipid droplets (LDs) has been studied extensively as a putative therapeutic target in diverse viral infections. However, directly targeting the LD lipolytic catabolism in virus-infected cells has not been widely investigated. Here, we show the linkage of the LD...

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Detalles Bibliográficos
Autores principales: Baek, Yeong-Bin, Kwon, Hyung-Jun, Sharif, Muhammad, Lim, Jeongah, Lee, In-Chul, Ryu, Young Bae, Lee, Jae-In, Kim, Ji-Sun, Lee, Young-Seung, Kim, Dong-Hoon, Park, Sang-Ik, Kim, Don-Kyu, Kim, Jeong-Sun, Choy, Hyon E., Lee, Sunwoo, Choi, Hueng-Sik, Osborne, Timothy F., Jeon, Tae-Il, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575645/
https://www.ncbi.nlm.nih.gov/pubmed/36253361
http://dx.doi.org/10.1038/s41392-022-01223-4

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