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Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (LUAD), the most common histological subtype, accounts for 40% of all cases. While existing genetically engineered mouse models (GEMMs) recapitulate the histological progression and transcriptional evolution of h...

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Detalles Bibliográficos
Autores principales:	Naranjo, Santiago, Cabana, Christina M., LaFave, Lindsay M., Romero, Rodrigo, Shanahan, Sean-Luc, Bhutkar, Arjun, Westcott, Peter M.K., Schenkel, Jason M., Ghosh, Arkopravo, Liao, Laura Z., Del Priore, Isabella, Yang, Dian, Jacks, Tyler
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Resource/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575694/ https://www.ncbi.nlm.nih.gov/pubmed/36175034 http://dx.doi.org/10.1101/gad.349659.122

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