Graves’ hyperthyroidism induced pancytopenia, epilepsia and muscle weakness: A case report

Pancytopenia and epilepsia are rare complications of Graves’ disease (GD). Muscle weakness is a physical sign of GD. It is extremely rare for GD patients to present 3 symptoms at the same time. PATIENT CONCERNS: A 35-year-old female was admitted to hospital for dizziness for 1 day. The results of laboratory examination on admission showed pancytopenia and hypothyroidism. Her clinical manifestations include pancytopenia, epilepsy, and muscle weakness. DIAGNOSIS: Graves’ hyperthyroidism. INTERVENTIONS: She received endotracheal intubation, ventilator, antithyroid drugs, and hormone therapy. OUTCOME: The patient was discharged after treatment. LESSON: Severe complications caused by GD are rare and require antithyroid therapy. Although glucocorticoid is not recommended by the guidelines, it can effectively improve thrombocytopenia.