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Continuous renal replacement therapy attenuates polymorphonuclear myeloid-derived suppressor cell expansion in pediatric severe sepsis

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) expansion is an important mechanism underlying immunosuppression during sepsis. Though continuous renal replacement therapy (CRRT) may attenuate hyperinflammatory response in sepsis, its role in regulating MDSCs is unknown. The aim of this study w...

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Detalles Bibliográficos
Autores principales: Feng, Shuyun, Cui, Yun, Zhou, Yiping, Shao, Lujing, Miao, Huijie, Dou, Jiaying, Liu, Tiantian, Wang, Chunxia, Zhang, Yucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575946/
https://www.ncbi.nlm.nih.gov/pubmed/36263056
http://dx.doi.org/10.3389/fimmu.2022.990522