Cellular interferon-gamma and interleukin-2 responses to SARS-CoV-2 structural proteins are broader and higher in those vaccinated after SARS-CoV-2 infection compared to vaccinees without prior SARS-CoV-2 infection

Class I- and Class II-restricted epitopes have been identified across the SARS-CoV-2 structural proteome. Vaccine-induced and post-infection SARS-CoV-2 T-cell responses are associated with COVID-19 recovery and protection, but the precise role of T-cell responses remains unclear, and how post-infect...

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Detalles Bibliográficos
Autores principales: Sedegah, Martha, Porter, Chad, Goguet, Emilie, Ganeshan, Harini, Belmonte, Maria, Huang, Jun, Belmonte, Arnel, Inoue, Sandra, Acheampong, Neda, Malloy, Allison M. W., Hollis-Perry, Monique, Jackson-Thompson, Belinda, Ramsey, Kathy F., Alcorta, Yolanda, Maiolatesi, Santina E., Wang, Gregory, Reyes, Anatolio E., Illinik, Luca, Sanchez-Edwards, Margaret, Burgess, Timothy H., Broder, Christopher C., Laing, Eric D., Pollett, Simon D., Villasante, Eileen, Mitre, Edward, Hollingdale, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576055/
https://www.ncbi.nlm.nih.gov/pubmed/36251675
http://dx.doi.org/10.1371/journal.pone.0276241

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