Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS

BACKGROUND: Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the pro-inflammatory alarmin HMGB1 (High-mobility group box 1). OBJECTIVE: The aim of this study was to explore the role of liquorice intake on the vira...

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Detalles Bibliográficos
Autores principales: Buder, Felix, Selejan, Simina-Ramona, Hohl, Mathias, Kindermann, Michael, Herr, Christian, Lepper, Philipp M., Bals, Robert, Salzberger, Bernd, Mahfoud, Felix, Böhm, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576069/
https://www.ncbi.nlm.nih.gov/pubmed/36251689
http://dx.doi.org/10.1371/journal.pone.0275181

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