Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model

Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disease caused by a trinucleotide CAG repeat. SCA7 predominantly causes a loss of photoreceptors in the retina and Purkinje cells of the cerebellum. Severe infantile-onset SCA7 also causes renal and cardiac irregularities. Previous reports...

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Detalles Bibliográficos
Autores principales: Miller, William, Pruett, Charles Lewis Humphrey, Stone, William, Eide, Cindy, Riddle, Megan, Popp, Courtney, Yousefzadeh, Matthew, Lees, Christopher, Seelig, Davis, Thompson, Elizabeth, Orr, Harry, Niedernhofer, Laura, Tolar, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576077/
https://www.ncbi.nlm.nih.gov/pubmed/36251631
http://dx.doi.org/10.1371/journal.pone.0275580

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