Cargando…

Consequences of PDGFRα(+) fibroblast reduction in adult murine hearts

Fibroblasts produce the majority of collagen in the heart and are thought to regulate extracellular matrix (ECM) turnover. Although fibrosis accompanies many cardiac pathologies and is generally deleterious, the role of fibroblasts in maintaining the basal ECM network and in fibrosis in vivo is poor...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuwabara, Jill T, Hara, Akitoshi, Bhutada, Sumit, Gojanovich, Greg S, Chen, Jasmine, Hokutan, Kanani, Shettigar, Vikram, Lee, Anson Y, DeAngelo, Lydia P, Heckl, Jack R, Jahansooz, Julia R, Tacdol, Dillon K, Ziolo, Mark T, Apte, Suneel S, Tallquist, Michelle D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576271/
https://www.ncbi.nlm.nih.gov/pubmed/36149056
http://dx.doi.org/10.7554/eLife.69854