Cargando…

A Novel Dextran-Based Dual Drug Conjugate Targeted Tumors with High Biodistribution Ratio of Tumors to Normal Tissues

PURPOSE: Most chemotherapeutic agents possess poor water solubility and show more significant accumulations in normal tissues than in tumor tissues, resulting in serious side effects. To this end, a novel dextran-based dual drug delivery system with high biodistribution ratio of tumors to normal tis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jiaojiao, Zhang, Naining, Wu, Jiaan, Dong, Peng, Lv, Hongshuai, Wang, Qi, Wang, Shenxu, Yang, Haotong, Wang, Si, Li, Xiaohai, Hu, Jinghua, Wang, Anny, Li, Daisy J, Shi, Yikang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576339/ https://www.ncbi.nlm.nih.gov/pubmed/36262192 http://dx.doi.org/10.2147/IJN.S379758

Ejemplares similares

Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells
por: Dong, Peng, et al.
Publicado: (2022)

Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids
por: Bitsch, Peter, et al.
Publicado: (2023)

A Novel Preparation Method for Camptothecin (CPT) Loaded Folic Acid Conjugated Dextran Tumor-Targeted Nanoparticles
por: Zu, Yuangang, et al.
Publicado: (2011)

Maleimidation of dextran and the application in designing a dextran–camptothecin conjugate
por: Zhu, Qiwen, et al.
Publicado: (2018)

Biodistribution of essential oil-conjugated silver nanoparticles
por: Gherasim, Oana, et al.
Publicado: (2020)

In vivo tumor targeting and imaging with anti-vascular endothelial growth factor antibody-conjugated dextran-coated iron oxide nanoparticles
por: Hsieh, Wan-Ju, et al.
Publicado: (2012)

Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma
por: Delrish, Elham, et al.
Publicado: (2022)

Brachytherapy Approach Using (177)Lu Conjugated Gold Nanostars and Evaluation of Biodistribution, Tumor Retention, Dosimetry and Therapeutic Efficacy in Head and Neck Tumor Model
por: Lin, Min-Ying, et al.
Publicado: (2021)

Modulating Pharmacokinetics, Tumor Uptake and Biodistribution by Engineered Nanoparticles
por: Arvizo, Rochelle R., et al.
Publicado: (2011)

Duodenal subepithelial neuroendocrine tumor removed by endoscopic submucosal dissection using internal traction with magnets
por: Baldaque-Silva, Francisco, et al.
Publicado: (2022)

Altered biodistribution of an antibody--enzyme conjugate modified with polyethylene glycol.
por: Eno-Amooquaye, E. A., et al.
Publicado: (1996)

Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
por: Baudhuin, Henri, et al.
Publicado: (2021)

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma
por: Cho, Nicholas, et al.
Publicado: (2021)

Microparticles of Sericin-Dextran Conjugate for Improving the Solubility of Antiviral Drug
por: Chen, Shuqi, et al.
Publicado: (2023)

Evaluation of Tumor Heterogeneity of Prostate Carcinoma by Flow- and Image DNA Cytometry and Histopathological Grading
por: Wang, Naining, et al.
Publicado: (2000)

Erratum: Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma
por: Delrish, Elham, et al.
Publicado: (2022)

Opposite Role of Tumor Necrosis Factor Receptors in Dextran Sulfate Sodium-Induced Colitis in Mice
por: Wang, Ke, et al.
Publicado: (2012)

Structural characteristics and emulsifying properties of myofibrillar protein-dextran conjugates induced by ultrasound Maillard reaction
por: Li, Zhiyu, et al.
Publicado: (2021)

Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles
por: Álamo, Patricia, et al.
Publicado: (2020)

Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking
por: Wang, Guankui, et al.
Publicado: (2016)

pH and Reduction Dual-Responsive Bi-Drugs Conjugated Dextran Assemblies for Combination Chemotherapy and In Vitro Evaluation
por: Xue, Xiukun, et al.
Publicado: (2021)

Effect of Catechol Content in Catechol-Conjugated Dextrans on Antiplatelet Performance
por: Jeong, Yeonwoo, et al.
Publicado: (2017)

Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354
por: Liu, Can, et al.
Publicado: (2019)

Apparent endocytosis of fluorescein isothiocyanate-conjugated dextran by Saccharomyces cerevisiae reflects uptake of low molecular weight impurities, not dextran
Publicado: (1987)

Tumor Localization and in vivo Antitumor Activity of the Immunoconjugate Composed of Anti‐human Colon Cancer Monoclonal Antibody and Mitomycin C‐Dextran Conjugate
por: Noguchi, Akinori, et al.
Publicado: (1991)

Microenvironment-triggered dual-activation of a photosensitizer- fluorophore conjugate for tumor specific imaging and photodynamic therapy
por: Wang, Chang, et al.
Publicado: (2020)

Enhanced tumor uptake, biodistribution and pharmacokinetics of etoposide loaded nanoparticles in Dalton's lymphoma tumor bearing mice
por: Snehalatha, Movva, et al.
Publicado: (2013)

Development of Alendronate-conjugated Poly (lactic-co-glycolic acid)-Dextran Nanoparticles for Active Targeting of Cisplatin in Osteosarcoma
por: Liu, Ping, et al.
Publicado: (2015)

Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution
por: Kim, Chang Hyun, et al.
Publicado: (2018)

Pituitary adenoma or pituitary neuroendocrine tumor: a narrative review of controversy and perspective
por: Liu, Xiaohai, et al.
Publicado: (2021)

Radioactive (198)Au-Doped Nanostructures with Different Shapes for In Vivo Analyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution
por: Black, Kvar C. L., et al.
Publicado: (2014)

Acitretin-Conjugated Dextran Nanoparticles Ameliorate Psoriasis-like Skin Disease at Low Dosages
por: Lan, Jiajia, et al.
Publicado: (2022)

Biodistribution and in Vivo Activities of Tumor-Associated Macrophage-Targeting Nanoparticles Incorporated with Doxorubicin
por: Niu, Mengmeng, et al.
Publicado: (2014)

Preparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting
por: Liu, Hui, et al.
Publicado: (2015)

CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody
por: Collado Camps, Estel, et al.
Publicado: (2021)

Chemosensitizing indomethacin-conjugated dextran-based micelles for effective delivery of paclitaxel in resistant breast cancer therapy
por: Ji, Weiping, et al.
Publicado: (2017)

Synthesis, Characterization, and Biodistribution of Quantum Dot-Celecoxib Conjugate in Mouse Paw Edema Model
por: Kalangi, Suresh K., et al.
Publicado: (2018)

A phase 0 study of the pharmacokinetics, biodistribution, and dosimetry of (188)Re-liposome in patients with metastatic tumors
por: Wang, Shyh-Jen, et al.
Publicado: (2019)

Retraction: Development of Alendronate-conjugated Poly (lactic-co-glycolic acid)-Dextran Nanoparticles for Active Targeting of Cisplatin in Osteosarcoma
por: Liu, Ping, et al.
Publicado: (2016)

DOTA-Functionalized Polylysine: A High Number of DOTA Chelates Positively Influences the Biodistribution of Enzymatic Conjugated Anti-Tumor Antibody chCE7agl
por: Grünberg, Jürgen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_f69ab3fh4hlrjpbu3qr38aec40