Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease

Dendritic cells (DCs) are the most important antigen-presenting cells and are pivotal in initiating effective adaptive immune responses to induce immune tolerance and maintain immune homeostasis. Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is chronic, int...

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Detalles Bibliográficos
Autores principales: Sun, Donglei, Li, Chenyang, Chen, Shuang, Zhang, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576373/
https://www.ncbi.nlm.nih.gov/pubmed/36262975
http://dx.doi.org/10.1155/2022/7025634
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author Sun, Donglei
Li, Chenyang
Chen, Shuang
Zhang, Xiaolan
author_facet Sun, Donglei
Li, Chenyang
Chen, Shuang
Zhang, Xiaolan
author_sort Sun, Donglei
collection PubMed
description Dendritic cells (DCs) are the most important antigen-presenting cells and are pivotal in initiating effective adaptive immune responses to induce immune tolerance and maintain immune homeostasis. Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is chronic, intestinal inflammatory and autoimmune disorder. DCs participate in IBD pathogenesis. This review is aimed at briefly discussing the role of DCs in IBD and the relationship between them and highlighting the prominent role of these cells in the treatment of these disorders.
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spelling pubmed-95763732022-10-18 Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease Sun, Donglei Li, Chenyang Chen, Shuang Zhang, Xiaolan Biomed Res Int Review Article Dendritic cells (DCs) are the most important antigen-presenting cells and are pivotal in initiating effective adaptive immune responses to induce immune tolerance and maintain immune homeostasis. Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is chronic, intestinal inflammatory and autoimmune disorder. DCs participate in IBD pathogenesis. This review is aimed at briefly discussing the role of DCs in IBD and the relationship between them and highlighting the prominent role of these cells in the treatment of these disorders. Hindawi 2022-10-10 /pmc/articles/PMC9576373/ /pubmed/36262975 http://dx.doi.org/10.1155/2022/7025634 Text en Copyright © 2022 Donglei Sun et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sun, Donglei
Li, Chenyang
Chen, Shuang
Zhang, Xiaolan
Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title_full Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title_fullStr Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title_full_unstemmed Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title_short Emerging Role of Dendritic Cell Intervention in the Treatment of Inflammatory Bowel Disease
title_sort emerging role of dendritic cell intervention in the treatment of inflammatory bowel disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576373/
https://www.ncbi.nlm.nih.gov/pubmed/36262975
http://dx.doi.org/10.1155/2022/7025634
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