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COVID-19–related clinical outcomes among Korean hemodialysis patients

BACKGROUND: Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 20...

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Autores principales: Park, Hayne Cho, Lee, Young-Ki, Ko, Eunsil, Yu, Sungbong, Cho, AJin, Kim, Do Hyoung, Kim, Jinseog, Cho, Jang-Hee, Lee, Jeonghwan, Kim, Dong Ki, Kim, Seong Nam, Yang, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576454/
https://www.ncbi.nlm.nih.gov/pubmed/35791744
http://dx.doi.org/10.23876/j.krcp.22.023
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author Park, Hayne Cho
Lee, Young-Ki
Ko, Eunsil
Yu, Sungbong
Cho, AJin
Kim, Do Hyoung
Kim, Jinseog
Cho, Jang-Hee
Lee, Jeonghwan
Kim, Dong Ki
Kim, Seong Nam
Yang, Chul-Woo
author_facet Park, Hayne Cho
Lee, Young-Ki
Ko, Eunsil
Yu, Sungbong
Cho, AJin
Kim, Do Hyoung
Kim, Jinseog
Cho, Jang-Hee
Lee, Jeonghwan
Kim, Dong Ki
Kim, Seong Nam
Yang, Chul-Woo
author_sort Park, Hayne Cho
collection PubMed
description BACKGROUND: Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 2019 (COVID-19) confirmed Korean HD patients. METHODS: From February 2020 to November 2021, the COVID-19 Task Force Team collected clinical data for HD patients with confirmed COVID-19 via a self-report survey of nephrologists. The composite outcome included in-hospital mortality, admission to the intensive care unit (ICU), and use of mechanical ventilation. Risk factors associated with clinical outcomes were analyzed among HD patients and compared to those of individuals without CKD using the COVID-19 database from the Korea Disease Control and Prevention Agency. RESULTS: A total of 380 HD patients from 206 facilities were diagnosed with COVID-19. Fever (49.5%) and cough (25.7%) were the two most common initial symptoms. The overall in-hospital fatality rate was 22.4% and even higher among ICU admission cases (64.7%). Non-survivors were older, more frequently developed shortness of breath, and were more likely to come from a nursing hospital. Compared to the age- and sex-matched non-CKD population, HD patients showed greater risk of in-hospital mortality (hazard ratio, 2.07; 95% confidence interval, 1.56–2.75; p < 0.001) and composite outcome (hazard ratio, 3.50; 95% confidence interval, 2.56–4.77; p < 0.001). CONCLUSION: HD patients have a greater risk of in-hospital mortality and morbidity from COVID-19. Special attention should be paid to COVID-19 HD patients when they are older or present with symptoms.
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spelling pubmed-95764542022-10-25 COVID-19–related clinical outcomes among Korean hemodialysis patients Park, Hayne Cho Lee, Young-Ki Ko, Eunsil Yu, Sungbong Cho, AJin Kim, Do Hyoung Kim, Jinseog Cho, Jang-Hee Lee, Jeonghwan Kim, Dong Ki Kim, Seong Nam Yang, Chul-Woo Kidney Res Clin Pract Original Article BACKGROUND: Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 2019 (COVID-19) confirmed Korean HD patients. METHODS: From February 2020 to November 2021, the COVID-19 Task Force Team collected clinical data for HD patients with confirmed COVID-19 via a self-report survey of nephrologists. The composite outcome included in-hospital mortality, admission to the intensive care unit (ICU), and use of mechanical ventilation. Risk factors associated with clinical outcomes were analyzed among HD patients and compared to those of individuals without CKD using the COVID-19 database from the Korea Disease Control and Prevention Agency. RESULTS: A total of 380 HD patients from 206 facilities were diagnosed with COVID-19. Fever (49.5%) and cough (25.7%) were the two most common initial symptoms. The overall in-hospital fatality rate was 22.4% and even higher among ICU admission cases (64.7%). Non-survivors were older, more frequently developed shortness of breath, and were more likely to come from a nursing hospital. Compared to the age- and sex-matched non-CKD population, HD patients showed greater risk of in-hospital mortality (hazard ratio, 2.07; 95% confidence interval, 1.56–2.75; p < 0.001) and composite outcome (hazard ratio, 3.50; 95% confidence interval, 2.56–4.77; p < 0.001). CONCLUSION: HD patients have a greater risk of in-hospital mortality and morbidity from COVID-19. Special attention should be paid to COVID-19 HD patients when they are older or present with symptoms. The Korean Society of Nephrology 2022-09 2022-06-21 /pmc/articles/PMC9576454/ /pubmed/35791744 http://dx.doi.org/10.23876/j.krcp.22.023 Text en Copyright © 2022 The Korean Society of Nephrology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial and No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) which permits unrestricted non-commercial use, distribution of the material without any modifications, and reproduction in any medium, provided the original works properly cited.
spellingShingle Original Article
Park, Hayne Cho
Lee, Young-Ki
Ko, Eunsil
Yu, Sungbong
Cho, AJin
Kim, Do Hyoung
Kim, Jinseog
Cho, Jang-Hee
Lee, Jeonghwan
Kim, Dong Ki
Kim, Seong Nam
Yang, Chul-Woo
COVID-19–related clinical outcomes among Korean hemodialysis patients
title COVID-19–related clinical outcomes among Korean hemodialysis patients
title_full COVID-19–related clinical outcomes among Korean hemodialysis patients
title_fullStr COVID-19–related clinical outcomes among Korean hemodialysis patients
title_full_unstemmed COVID-19–related clinical outcomes among Korean hemodialysis patients
title_short COVID-19–related clinical outcomes among Korean hemodialysis patients
title_sort covid-19–related clinical outcomes among korean hemodialysis patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576454/
https://www.ncbi.nlm.nih.gov/pubmed/35791744
http://dx.doi.org/10.23876/j.krcp.22.023
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