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Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza

CULLIN (CUL) proteins are E3 ubiquitin ligases that are involved in a wide variety of biological processes as well as in response to stress in plants. In Salvia miltiorrhiza, CUL genes have not been characterized and its role in plant development, stress response and secondary metabolite synthesis h...

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Autores principales: Gao, Xiankui, Li, Xiujuan, Chen, Chengan, Wang, Can, Fu, Yuqi, Zheng, ZiZhen, Shi, Min, Hao, Xiaolong, Zhao, Limei, Qiu, Minghua, Kai, Guoyin, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576582/
https://www.ncbi.nlm.nih.gov/pubmed/36268136
http://dx.doi.org/10.1016/j.crfs.2022.10.011
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author Gao, Xiankui
Li, Xiujuan
Chen, Chengan
Wang, Can
Fu, Yuqi
Zheng, ZiZhen
Shi, Min
Hao, Xiaolong
Zhao, Limei
Qiu, Minghua
Kai, Guoyin
Zhou, Wei
author_facet Gao, Xiankui
Li, Xiujuan
Chen, Chengan
Wang, Can
Fu, Yuqi
Zheng, ZiZhen
Shi, Min
Hao, Xiaolong
Zhao, Limei
Qiu, Minghua
Kai, Guoyin
Zhou, Wei
author_sort Gao, Xiankui
collection PubMed
description CULLIN (CUL) proteins are E3 ubiquitin ligases that are involved in a wide variety of biological processes as well as in response to stress in plants. In Salvia miltiorrhiza, CUL genes have not been characterized and its role in plant development, stress response and secondary metabolite synthesis have not been studied. In this study, genome-wide analyses were performed to identify and to predict the structure and function of CUL of S. miltiorrhiza. Eight CUL genes were identified from the genome of S. miltiorrhiza. The CUL genes were clustered into four subgroups according to phylogenetic relationships. The CUL domain was highly conserved across the family of CUL genes. Analysis of cis-acting elements suggested that CUL genes might play important roles in a variety of biological processes, including abscission reaction acid (ABA) processing. To investigate this hypothesis, we treated hairy roots of S. miltiorrhiza with ABA. The expression of CUL genes varied obviously after ABA treatment. Co-expression network results indicated that three CUL genes might be involved in the biosynthesis of phenolic acid or tanshinone. In summary, the mining of the CUL genes in the whole genome of S. miltiorrhiza contribute novel information to the understanding of the CUL genes and its functional roles in plant secondary metabolites, growth and development.
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spelling pubmed-95765822022-10-19 Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza Gao, Xiankui Li, Xiujuan Chen, Chengan Wang, Can Fu, Yuqi Zheng, ZiZhen Shi, Min Hao, Xiaolong Zhao, Limei Qiu, Minghua Kai, Guoyin Zhou, Wei Curr Res Food Sci Articles from the special issue: 6th International Symposium on Phytochemicals in Medicine and Food, edited by Jianbo Xiao, Jinping Si and Huifan Liu CULLIN (CUL) proteins are E3 ubiquitin ligases that are involved in a wide variety of biological processes as well as in response to stress in plants. In Salvia miltiorrhiza, CUL genes have not been characterized and its role in plant development, stress response and secondary metabolite synthesis have not been studied. In this study, genome-wide analyses were performed to identify and to predict the structure and function of CUL of S. miltiorrhiza. Eight CUL genes were identified from the genome of S. miltiorrhiza. The CUL genes were clustered into four subgroups according to phylogenetic relationships. The CUL domain was highly conserved across the family of CUL genes. Analysis of cis-acting elements suggested that CUL genes might play important roles in a variety of biological processes, including abscission reaction acid (ABA) processing. To investigate this hypothesis, we treated hairy roots of S. miltiorrhiza with ABA. The expression of CUL genes varied obviously after ABA treatment. Co-expression network results indicated that three CUL genes might be involved in the biosynthesis of phenolic acid or tanshinone. In summary, the mining of the CUL genes in the whole genome of S. miltiorrhiza contribute novel information to the understanding of the CUL genes and its functional roles in plant secondary metabolites, growth and development. Elsevier 2022-10-08 /pmc/articles/PMC9576582/ /pubmed/36268136 http://dx.doi.org/10.1016/j.crfs.2022.10.011 Text en © 2022 The Authors. Published by Elsevier B.V. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Articles from the special issue: 6th International Symposium on Phytochemicals in Medicine and Food, edited by Jianbo Xiao, Jinping Si and Huifan Liu
Gao, Xiankui
Li, Xiujuan
Chen, Chengan
Wang, Can
Fu, Yuqi
Zheng, ZiZhen
Shi, Min
Hao, Xiaolong
Zhao, Limei
Qiu, Minghua
Kai, Guoyin
Zhou, Wei
Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title_full Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title_fullStr Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title_full_unstemmed Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title_short Mining of the CULLIN E3 ubiquitin ligase genes in the whole genome of Salvia miltiorrhiza
title_sort mining of the cullin e3 ubiquitin ligase genes in the whole genome of salvia miltiorrhiza
topic Articles from the special issue: 6th International Symposium on Phytochemicals in Medicine and Food, edited by Jianbo Xiao, Jinping Si and Huifan Liu
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576582/
https://www.ncbi.nlm.nih.gov/pubmed/36268136
http://dx.doi.org/10.1016/j.crfs.2022.10.011
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