A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies

Rationale: The blood-brain barrier (BBB) is a major impediment to therapeutic intracranial drug delivery for the treatment of neurodegenerative diseases, including Alzheimer's disease (AD). Focused ultrasound applied together with microbubbles (FUS(+MB)) is a novel technique to transiently open...

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Detalles Bibliográficos
Autores principales: Wasielewska, Joanna M., Chaves, Juliana C. S., Johnston, Rebecca L., Milton, Laura A., Hernández, Damián, Chen, Liyu, Song, Jae, Lee, Wendy, Leinenga, Gerhard, Nisbet, Rebecca M., Pébay, Alice, Götz, Jürgen, White, Anthony R., Oikari, Lotta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576609/
https://www.ncbi.nlm.nih.gov/pubmed/36276649
http://dx.doi.org/10.7150/thno.72685

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