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TCA-phospholipid-glycolysis targeted triple therapy effectively suppresses ATP production and tumor growth in glioblastoma

Rationale: Glioblastoma (GBM) displays a complex metabolic reprogramming in cancer cells. Adenosine triphosphate (ATP) is one of the central mediators of cell metabolism and signaling. GBM cells generate ATP by glycolysis and the tricarboxylic acid (TCA) cycle associated with oxidative phosphorylati...

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Detalles Bibliográficos
Autores principales: Yang, Shixue, Zhao, Jixing, Cui, Xiaoteng, Zhan, Qi, Yi, Kaikai, Wang, Qixue, Xiao, Menglin, Tan, Yanli, Hong, Biao, Fang, Chuan, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576613/
https://www.ncbi.nlm.nih.gov/pubmed/36276638
http://dx.doi.org/10.7150/thno.74197