Yap1 modulates cardiomyocyte hypertrophy via impaired mitochondrial biogenesis in response to chronic mechanical stress overload

Rationale: Chronic pressure overload is a major trigger of cardiac pathological hypertrophy that eventually leads to heart disease and heart failure. Understanding the mechanisms governing hypertrophy is the key to develop therapeutic strategies for heart diseases. Methods: We built chronic pressure...

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Detalles Bibliográficos
Autores principales: Yue, Peng, Zhang, Yue, Liu, Lei, Zhou, Kaiyu, Xia, Shutao, Peng, Mou, Yan, Hualin, Tang, Xiaoqiang, Chen, Zhan, Zhang, Donghui, Guo, Junling, Pu, William T., Guo, Yuxuan, Hua, Yimin, Li, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576622/
https://www.ncbi.nlm.nih.gov/pubmed/36276651
http://dx.doi.org/10.7150/thno.74563

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