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The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair

SUMMARY: Due to the high burden of fragility fractures, we developed an interdisciplinary FLS care pathway for early management and monitoring of older adults discharged from a high-volume trauma center after hip fracture repair. Interdisciplinary FLS effectively improves up to 1-year adherence to t...

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Autores principales: Ruggiero, Carmelinda, Baroni, Marta, Talesa, Giuseppe Rocco, Cirimbilli, Alessandro, Prenni, Valentina, Bubba, Valentina, Parretti, Luca, Bogini, Riccardo, Duranti, Giuliana, Caraffa, Auro, Boccardi, Virginia, Mecocci, Patrizia, Rinonapoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576663/
https://www.ncbi.nlm.nih.gov/pubmed/36251126
http://dx.doi.org/10.1007/s11657-022-01171-0
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author Ruggiero, Carmelinda
Baroni, Marta
Talesa, Giuseppe Rocco
Cirimbilli, Alessandro
Prenni, Valentina
Bubba, Valentina
Parretti, Luca
Bogini, Riccardo
Duranti, Giuliana
Caraffa, Auro
Boccardi, Virginia
Mecocci, Patrizia
Rinonapoli, Giuseppe
author_facet Ruggiero, Carmelinda
Baroni, Marta
Talesa, Giuseppe Rocco
Cirimbilli, Alessandro
Prenni, Valentina
Bubba, Valentina
Parretti, Luca
Bogini, Riccardo
Duranti, Giuliana
Caraffa, Auro
Boccardi, Virginia
Mecocci, Patrizia
Rinonapoli, Giuseppe
author_sort Ruggiero, Carmelinda
collection PubMed
description SUMMARY: Due to the high burden of fragility fractures, we developed an interdisciplinary FLS care pathway for early management and monitoring of older adults discharged from a high-volume trauma center after hip fracture repair. Interdisciplinary FLS effectively improves up to 1-year adherence to treatments for secondary prevention of fragility fractures, reduces health facility admission, and improves long-term survival. PURPOSE: To compare adherence to secondary fragility fracture prevention, falls, healthcare facility admissions, and mortality between hip fracture older adults who entered the fracture liaison services pathway of care (FLS-CP) and those managed according to the usual traumatologist model of care (U-CP). METHODS: Prospective observational study enrolling subjects aged ≥ 65 years discharged by high-volume trauma center after hip fracture repair from February 2016 to February 2017, who consecutively entered FLS-CP or U-CP according to their preference and goals. RESULTS: Compared to U-CP, those in FLS-CP had higher initiation rate and up to 1-year adherence to secondary prevention of fragility fracture, including vitamin D and calcium (87.7% vs 36.9%; p < 0.0001), specific anti-osteoporosis drugs (75.1% vs 8.0%; p < 0.0001), and complete anti-fracture therapy (72.3% vs 5.7%; p < 0.0001). Older adults belonging to FLS-CP showed a lower likelihood of healthcare facility admission (RR 0.597; 95% CI 0.398–0.895; p = 0.0125), with a longer re-hospitalization-free survival (176.4 vs 88.7 days; p = 0.0152) than those in U-CP. One-year incidence of falls and fractures was similar between groups, with a lower tendency of the subjects in the FLS-CP to be multiple fallers (19% vs 34.8%; OR 0.057; 95% CI 0.004–0.876; p = 0.0690). The FLS-CP group experienced a lower 1-year (87.2% vs 74.3%; p = 0.001) and 3-year mortality (67.9% vs 55.6%; p = 0.0245) and a lower adjusted 5-year mortality hazard ratio (50.2% vs 58%; HR = 0.76; 95% CI 0.60; 0.96). CONCLUSION: The FLS-CP may improve initiation and adherence to secondary prevention of fragility fractures, reduces healthcare facility admission, and improves long-term survival. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11657-022-01171-0.
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spelling pubmed-95766632022-10-19 The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair Ruggiero, Carmelinda Baroni, Marta Talesa, Giuseppe Rocco Cirimbilli, Alessandro Prenni, Valentina Bubba, Valentina Parretti, Luca Bogini, Riccardo Duranti, Giuliana Caraffa, Auro Boccardi, Virginia Mecocci, Patrizia Rinonapoli, Giuseppe Arch Osteoporos Original Article SUMMARY: Due to the high burden of fragility fractures, we developed an interdisciplinary FLS care pathway for early management and monitoring of older adults discharged from a high-volume trauma center after hip fracture repair. Interdisciplinary FLS effectively improves up to 1-year adherence to treatments for secondary prevention of fragility fractures, reduces health facility admission, and improves long-term survival. PURPOSE: To compare adherence to secondary fragility fracture prevention, falls, healthcare facility admissions, and mortality between hip fracture older adults who entered the fracture liaison services pathway of care (FLS-CP) and those managed according to the usual traumatologist model of care (U-CP). METHODS: Prospective observational study enrolling subjects aged ≥ 65 years discharged by high-volume trauma center after hip fracture repair from February 2016 to February 2017, who consecutively entered FLS-CP or U-CP according to their preference and goals. RESULTS: Compared to U-CP, those in FLS-CP had higher initiation rate and up to 1-year adherence to secondary prevention of fragility fracture, including vitamin D and calcium (87.7% vs 36.9%; p < 0.0001), specific anti-osteoporosis drugs (75.1% vs 8.0%; p < 0.0001), and complete anti-fracture therapy (72.3% vs 5.7%; p < 0.0001). Older adults belonging to FLS-CP showed a lower likelihood of healthcare facility admission (RR 0.597; 95% CI 0.398–0.895; p = 0.0125), with a longer re-hospitalization-free survival (176.4 vs 88.7 days; p = 0.0152) than those in U-CP. One-year incidence of falls and fractures was similar between groups, with a lower tendency of the subjects in the FLS-CP to be multiple fallers (19% vs 34.8%; OR 0.057; 95% CI 0.004–0.876; p = 0.0690). The FLS-CP group experienced a lower 1-year (87.2% vs 74.3%; p = 0.001) and 3-year mortality (67.9% vs 55.6%; p = 0.0245) and a lower adjusted 5-year mortality hazard ratio (50.2% vs 58%; HR = 0.76; 95% CI 0.60; 0.96). CONCLUSION: The FLS-CP may improve initiation and adherence to secondary prevention of fragility fractures, reduces healthcare facility admission, and improves long-term survival. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11657-022-01171-0. Springer London 2022-10-17 2022 /pmc/articles/PMC9576663/ /pubmed/36251126 http://dx.doi.org/10.1007/s11657-022-01171-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Ruggiero, Carmelinda
Baroni, Marta
Talesa, Giuseppe Rocco
Cirimbilli, Alessandro
Prenni, Valentina
Bubba, Valentina
Parretti, Luca
Bogini, Riccardo
Duranti, Giuliana
Caraffa, Auro
Boccardi, Virginia
Mecocci, Patrizia
Rinonapoli, Giuseppe
The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title_full The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title_fullStr The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title_full_unstemmed The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title_short The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
title_sort interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576663/
https://www.ncbi.nlm.nih.gov/pubmed/36251126
http://dx.doi.org/10.1007/s11657-022-01171-0
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