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Characterizing the composition of iPSC derived cells from bulk transcriptomics data with CellMap

Induced pluripotent stem cell (iPSC) derived cell types are increasingly employed as in vitro model systems for drug discovery. For these studies to be meaningful, it is important to understand the reproducibility of the iPSC-derived cultures and their similarity to equivalent endogenous cell types....

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Detalles Bibliográficos
Autores principales: Ouyang, Zhengyu, Bourgeois-Tchir, Nathanael, Lyashenko, Eugenia, Cundiff, Paige E., Cullen, Patrick F., Challa, Ravi, Li, Kejie, Zhang, Xinmin, Casey, Fergal, Engle, Sandra J., Zhang, Baohong, Zavodszky, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576729/
https://www.ncbi.nlm.nih.gov/pubmed/36253414
http://dx.doi.org/10.1038/s41598-022-22115-1