Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile

Some bacteria express a binary toxin translocation system, consisting of an enzymatic subunit and translocation pore, that delivers enzymes into host cells through endocytosis. The most clinically important bacterium with such a system is Clostridioides difficile (formerly Clostridium). The CDTa and...

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Detalles Bibliográficos
Autores principales: Kawamoto, Akihiro, Yamada, Tomohito, Yoshida, Toru, Sato, Yusui, Kato, Takayuki, Tsuge, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576733/
https://www.ncbi.nlm.nih.gov/pubmed/36253419
http://dx.doi.org/10.1038/s41467-022-33888-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576733/
https://www.ncbi.nlm.nih.gov/pubmed/36253419
http://dx.doi.org/10.1038/s41467-022-33888-4

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