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Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile
Some bacteria express a binary toxin translocation system, consisting of an enzymatic subunit and translocation pore, that delivers enzymes into host cells through endocytosis. The most clinically important bacterium with such a system is Clostridioides difficile (formerly Clostridium). The CDTa and...
Autores principales: | Kawamoto, Akihiro, Yamada, Tomohito, Yoshida, Toru, Sato, Yusui, Kato, Takayuki, Tsuge, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576733/ https://www.ncbi.nlm.nih.gov/pubmed/36253419 http://dx.doi.org/10.1038/s41467-022-33888-4 |
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