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CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer’s disease

To test whether cerebrospinal fluid (CSF) growth-associated protein 43 (GAP-43) concentration is elevated in Alzheimer’s disease (AD) dementia and its associations with other hallmarks of AD, we examined the CSF GAP-43 measurements of 787 participants (245 cognitively normal (CN), 415 individuals wi...

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Detalles Bibliográficos
Autores principales: Qiang, Qiang, Skudder-Hill, Loren, Toyota, Tomoko, Wei, Wenshi, Adachi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576773/
https://www.ncbi.nlm.nih.gov/pubmed/36253408
http://dx.doi.org/10.1038/s41598-022-20324-2