Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis

Cell migration regulates diverse (patho)physiological processes, including cancer metastasis. According to the Osmotic Engine Model, polarization of NHE1 at the leading edge of confined cells facilitates water uptake, cell protrusion and motility. The physiological relevance of the Osmotic Engine Mo...

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Detalles Bibliográficos
Autores principales: Zhang, Yuqi, Li, Yizeng, Thompson, Keyata N., Stoletov, Konstantin, Yuan, Qinling, Bera, Kaustav, Lee, Se Jong, Zhao, Runchen, Kiepas, Alexander, Wang, Yao, Mistriotis, Panagiotis, Serra, Selma A., Lewis, John D., Valverde, Miguel A., Martin, Stuart S., Sun, Sean X., Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576788/
https://www.ncbi.nlm.nih.gov/pubmed/36253369
http://dx.doi.org/10.1038/s41467-022-33683-1

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