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NQO1 protects against clioquinol toxicity
Clioquinol (CQ) was widely used as oral antibiotic before being taken off the market in many countries in 1970, after it was linked to subacute myelo-optic neuropathy (SMON) in Japan, leading to vision loss with many patients left wheelchair-bound. The common pathology of CQ-associated SMON was repr...
Autores principales: | Chhetri, Jamuna, Dilek, Jem, Davies, Noel, Jacobson, Glenn, Dallmann, Robert, Gueven, Nuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576850/ https://www.ncbi.nlm.nih.gov/pubmed/36267290 http://dx.doi.org/10.3389/fphar.2022.1000278 |
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