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Loss of Anti-Müllerian Hormone Signaling in Mice Affects Trabecular Bone Mass in a Sex- and Age-Dependent Manner

Ovariectomy-induced osteoporosis in mice results from an abrupt loss of ovarian sex steroids. Anti-Müllerian hormone knockout (AMHKO) mice show a gradual but accelerated ovarian aging, and therefore may better resemble osteoporosis following natural menopause. To study the impact of AMH signaling de...

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Detalles Bibliográficos
Autores principales: van As, Christiane, Koedam, Marijke, McLuskey, Anke, Kramer, Piet, Lahlou, Najiba, van der Eerden, Bram C J, Visser, Jenny A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576916/
https://www.ncbi.nlm.nih.gov/pubmed/36155779
http://dx.doi.org/10.1210/endocr/bqac157