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A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4(+) T lymphocytes in unexposed individuals

Circulating, blood-borne SARS-CoV-2-reactive memory T cells in persons so far unexposed to SARS-CoV-2 or the vaccines have been described in 20-100% of the adult population. They are credited with determining the efficacy of the immune response in COVID-19. Here, we demonstrate the presence of preex...

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Detalles Bibliográficos
Autores principales: Li, Jinchan, Reinke, Simon, Shen, Yu, Schollmeyer, Lena, Liu, Yuk-Chien, Wang, Zixu, Hardt, Sebastian, Hipfl, Christian, Hoffmann, Ute, Frischbutter, Stefan, Chang, Hyun-Dong, Alexander, Tobias, Perka, Carsten, Radbruch, Helena, Qin, Zhihai, Radbruch, Andreas, Dong, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576920/
https://www.ncbi.nlm.nih.gov/pubmed/36268016
http://dx.doi.org/10.3389/fimmu.2022.1004656