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Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review
Guillain–Barré syndrome (GBS) is a potentially life-threatening post-infectious autoimmune disease characterized by rapidly progressive symmetrical weakness of the extremities. Herein, we report a case of GBS associated with drug poisoning complicated by Klebsiella pneumoniae infection. A 38-year-ol...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576939/ https://www.ncbi.nlm.nih.gov/pubmed/36267621 http://dx.doi.org/10.3389/fmed.2022.991182 |
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author | Zhang, Boyu Duan, Liwei Ma, Linhao Cai, Qingqing Wu, Hao Chang, Liang Li, Wenfang Lin, Zhaofen |
author_facet | Zhang, Boyu Duan, Liwei Ma, Linhao Cai, Qingqing Wu, Hao Chang, Liang Li, Wenfang Lin, Zhaofen |
author_sort | Zhang, Boyu |
collection | PubMed |
description | Guillain–Barré syndrome (GBS) is a potentially life-threatening post-infectious autoimmune disease characterized by rapidly progressive symmetrical weakness of the extremities. Herein, we report a case of GBS associated with drug poisoning complicated by Klebsiella pneumoniae infection. A 38-year-old woman was admitted to the intensive care unit after taking an overdose of amitriptyline and was later diagnosed with coma, Klebsiella pneumoniae infection, and septic shock. Thirteen days after admission, she was diagnosed with GBS based on acute muscle pain, flaccid paralysis, hyporeflexia, reduced amplitude of compound muscle action potential, and albuminocytologic dissociation in the cerebrospinal fluid. GBS rarely occurs after a drug overdose and septic shock, and this is the first report of a rapidly progressive GBS following amitriptyline overdose and severe Klebsiella pneumoniae infection. |
format | Online Article Text |
id | pubmed-9576939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95769392022-10-19 Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review Zhang, Boyu Duan, Liwei Ma, Linhao Cai, Qingqing Wu, Hao Chang, Liang Li, Wenfang Lin, Zhaofen Front Med (Lausanne) Medicine Guillain–Barré syndrome (GBS) is a potentially life-threatening post-infectious autoimmune disease characterized by rapidly progressive symmetrical weakness of the extremities. Herein, we report a case of GBS associated with drug poisoning complicated by Klebsiella pneumoniae infection. A 38-year-old woman was admitted to the intensive care unit after taking an overdose of amitriptyline and was later diagnosed with coma, Klebsiella pneumoniae infection, and septic shock. Thirteen days after admission, she was diagnosed with GBS based on acute muscle pain, flaccid paralysis, hyporeflexia, reduced amplitude of compound muscle action potential, and albuminocytologic dissociation in the cerebrospinal fluid. GBS rarely occurs after a drug overdose and septic shock, and this is the first report of a rapidly progressive GBS following amitriptyline overdose and severe Klebsiella pneumoniae infection. Frontiers Media S.A. 2022-10-04 /pmc/articles/PMC9576939/ /pubmed/36267621 http://dx.doi.org/10.3389/fmed.2022.991182 Text en Copyright © 2022 Zhang, Duan, Ma, Cai, Wu, Chang, Li and Lin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Zhang, Boyu Duan, Liwei Ma, Linhao Cai, Qingqing Wu, Hao Chang, Liang Li, Wenfang Lin, Zhaofen Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title | Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title_full | Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title_fullStr | Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title_full_unstemmed | Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title_short | Rapidly progressive Guillain–Barré syndrome following amitriptyline overdose and severe Klebsiella pneumoniae infection: A case report and literature review |
title_sort | rapidly progressive guillain–barré syndrome following amitriptyline overdose and severe klebsiella pneumoniae infection: a case report and literature review |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576939/ https://www.ncbi.nlm.nih.gov/pubmed/36267621 http://dx.doi.org/10.3389/fmed.2022.991182 |
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