A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure

A 5-year-old girl presented to the emergency room with altered mental status secondary to severe diabetic ketoacidosis due to new-onset GAD65 antibody positive, type 1 diabetes mellitus. On hospital day 0, she developed anuria, shock, and hypertriglyceridemia-associated acute pancreatitis. Following...

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Detalles Bibliográficos
Autores principales: Alexander, Seth M, Shenoy, Vivek, Kihlstrom, Margaret, Levenson, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577081/
https://www.ncbi.nlm.nih.gov/pubmed/36267335
http://dx.doi.org/10.1177/2050313X221130582
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author Alexander, Seth M
Shenoy, Vivek
Kihlstrom, Margaret
Levenson, Amy
author_facet Alexander, Seth M
Shenoy, Vivek
Kihlstrom, Margaret
Levenson, Amy
author_sort Alexander, Seth M
collection PubMed
description A 5-year-old girl presented to the emergency room with altered mental status secondary to severe diabetic ketoacidosis due to new-onset GAD65 antibody positive, type 1 diabetes mellitus. On hospital day 0, she developed anuria, shock, and hypertriglyceridemia-associated acute pancreatitis. Following intravenous insulin therapy, the patient’s ketoacidosis improved. Her other complications persisted for several days and improved only with significant fluid resuscitation and supportive interventions, including intubation, thoracostomy, and vasopressors. This case underscores the importance of recognizing the early warning signs of diabetic ketoacidosis and reviews how to appropriately manage its associated life-threatening complications.
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spelling pubmed-95770812022-10-19 A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure Alexander, Seth M Shenoy, Vivek Kihlstrom, Margaret Levenson, Amy SAGE Open Med Case Rep Case Report A 5-year-old girl presented to the emergency room with altered mental status secondary to severe diabetic ketoacidosis due to new-onset GAD65 antibody positive, type 1 diabetes mellitus. On hospital day 0, she developed anuria, shock, and hypertriglyceridemia-associated acute pancreatitis. Following intravenous insulin therapy, the patient’s ketoacidosis improved. Her other complications persisted for several days and improved only with significant fluid resuscitation and supportive interventions, including intubation, thoracostomy, and vasopressors. This case underscores the importance of recognizing the early warning signs of diabetic ketoacidosis and reviews how to appropriately manage its associated life-threatening complications. SAGE Publications 2022-10-15 /pmc/articles/PMC9577081/ /pubmed/36267335 http://dx.doi.org/10.1177/2050313X221130582 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Alexander, Seth M
Shenoy, Vivek
Kihlstrom, Margaret
Levenson, Amy
A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title_full A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title_fullStr A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title_full_unstemmed A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title_short A 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
title_sort 5-year-old with new-onset diabetes presenting with ketoacidosis, acute pancreatitis, and renal failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577081/
https://www.ncbi.nlm.nih.gov/pubmed/36267335
http://dx.doi.org/10.1177/2050313X221130582
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