Cargando…
Structure‒function‒pathogenicity analysis of C-terminal myocilin missense variants based on experiments and 3D models
MYOC is a common pathogenic gene for primary open-angle glaucoma and encodes the protein named myocilin. Multiple MYOC variations have been found, with different clinical significance. However, the pathogenesis of glaucoma induced by MYOC mutations has not been fully clarified. Here, we analyze the...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577182/ https://www.ncbi.nlm.nih.gov/pubmed/36267417 http://dx.doi.org/10.3389/fgene.2022.1019208 |