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Spermidine Promotes Nb CAR-T Mediated Cytotoxicity to Lymphoma Cells Through Elevating Proliferation and Memory

PURPOSE: Due to the natural advantages of spermidine in immunity, we investigated the effects of spermidine pretreatment on nanobody-based CAR-T cells (Nb CAR-T) mediated cytotoxicity and potential mechanism. PATIENTS AND METHODS: The optimal concentration of spermidine was determined by detecting i...

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Detalles Bibliográficos
Autores principales:	Wang, Hongxia, Jiang, Dan, Liu, Liyuan, Zhang, Yanting, Qin, Miao, Qu, Yuliang, Wang, Liyan, Wu, Shan, Zhou, Haijin, Xu, Tao, Xu, Guangxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577380/ https://www.ncbi.nlm.nih.gov/pubmed/36267609 http://dx.doi.org/10.2147/OTT.S382540

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