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Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults

This proof-of-concept study tested if prior BCG revaccination can qualitatively and quantitively enhance antibody and T-cell responses induced by Oxford/AstraZeneca ChAdOx1nCoV-19 or COVISHIELD™, an efficacious and the most widely distributed vaccine in India. We compared COVISHIELD™ induced longitu...

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Detalles Bibliográficos
Autores principales: Rakshit, Srabanti, Adiga, Vasista, Ahmed, Asma, Parthiban, Chaitra, Chetan Kumar, Nirutha, Dwarkanath, Pratibha, Shivalingaiah, Sudarshan, Rao, Srishti, D’Souza, George, Dias, Mary, Maguire, Thomas J. A., Doores, Katie J., Zoodsma, Martijn, Geckin, Busranur, Dasgupta, Prokar, Babji, Sudhir, van Meijgaarden, Krista E., Joosten, Simone A., Ottenhoff, Tom H. M., Li, Yang, Netea, Mihai G., Stuart, Kenneth D., De Rosa, Stephen C., McElrath, M. Juliana, Vyakarnam, Annapurna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577398/
https://www.ncbi.nlm.nih.gov/pubmed/36268023
http://dx.doi.org/10.3389/fimmu.2022.985938