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Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature

INTRODUCTION AND IMPORTANCE: Filiform polyposis, a rare condition also referred to as inflammatory polyposis or pseudopolyposis, is commonly observed in cases of inflammatory bowel disease, such as ulcerative colitis or Crohn's disease. It is generally considered a benign tumour characterised b...

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Autores principales: Kasuga, So, Anzai, Hiroyuki, Makise, Naohiro, Sonoda, Hirofumi, Nagai, Yuzo, Abe, Shinya, Yokoyama, Yuichiro, Ozawa, Tsuyoshi, Emoto, Shigenobu, Murono, Koji, Sasaki, Kazuhito, Kawai, Kazushige, Nozawa, Hiroaki, Ushiku, Tetsuo, Ishihara, Soichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577439/
https://www.ncbi.nlm.nih.gov/pubmed/36268352
http://dx.doi.org/10.1016/j.amsu.2022.104433
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author Kasuga, So
Anzai, Hiroyuki
Makise, Naohiro
Sonoda, Hirofumi
Nagai, Yuzo
Abe, Shinya
Yokoyama, Yuichiro
Ozawa, Tsuyoshi
Emoto, Shigenobu
Murono, Koji
Sasaki, Kazuhito
Kawai, Kazushige
Nozawa, Hiroaki
Ushiku, Tetsuo
Ishihara, Soichiro
author_facet Kasuga, So
Anzai, Hiroyuki
Makise, Naohiro
Sonoda, Hirofumi
Nagai, Yuzo
Abe, Shinya
Yokoyama, Yuichiro
Ozawa, Tsuyoshi
Emoto, Shigenobu
Murono, Koji
Sasaki, Kazuhito
Kawai, Kazushige
Nozawa, Hiroaki
Ushiku, Tetsuo
Ishihara, Soichiro
author_sort Kasuga, So
collection PubMed
description INTRODUCTION AND IMPORTANCE: Filiform polyposis, a rare condition also referred to as inflammatory polyposis or pseudopolyposis, is commonly observed in cases of inflammatory bowel disease, such as ulcerative colitis or Crohn's disease. It is generally considered a benign tumour characterised by multiple finger-like projections that are mostly observed in the transverse and descending colon. CASE PRESENTATION: A 69-year-old woman with a history of ulcerative colitis for 18 years who underwent temporary decompression ileostomy for large bowel obstruction at another hospital was referred to our institution for further investigation. Abdominal computed tomography revealed bowel wall thickening of the transverse colon, and colonoscopy revealed stenosis in the hepatic flexure obstructing the endoscope. Although several biopsies of the tumour showed no malignancy, laparoscopic subtotal colectomy with lymph node dissection was performed. Histopathological findings revealed localised filiform polyposis with dysplasia. CLINICAL DISCUSSION: Filiform polyposis has been considered a benign inflammatory polyp without any risk of dysplasia. We accumulated previous cases of giant filiform polyposis and reviewed their characteristics. The presented case of filiform polyposis with ulcerative colitis complicated with high-grade dysplasia highlights the importance of considering malignancy in patients with filiform polyposis. CONCLUSION: In cases of giant filiform polyposis, even when no malignancy is detected, surgical resection should be considered for the possibility of a malignant component of dysplasia.
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spelling pubmed-95774392022-10-19 Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature Kasuga, So Anzai, Hiroyuki Makise, Naohiro Sonoda, Hirofumi Nagai, Yuzo Abe, Shinya Yokoyama, Yuichiro Ozawa, Tsuyoshi Emoto, Shigenobu Murono, Koji Sasaki, Kazuhito Kawai, Kazushige Nozawa, Hiroaki Ushiku, Tetsuo Ishihara, Soichiro Ann Med Surg (Lond) Case Report INTRODUCTION AND IMPORTANCE: Filiform polyposis, a rare condition also referred to as inflammatory polyposis or pseudopolyposis, is commonly observed in cases of inflammatory bowel disease, such as ulcerative colitis or Crohn's disease. It is generally considered a benign tumour characterised by multiple finger-like projections that are mostly observed in the transverse and descending colon. CASE PRESENTATION: A 69-year-old woman with a history of ulcerative colitis for 18 years who underwent temporary decompression ileostomy for large bowel obstruction at another hospital was referred to our institution for further investigation. Abdominal computed tomography revealed bowel wall thickening of the transverse colon, and colonoscopy revealed stenosis in the hepatic flexure obstructing the endoscope. Although several biopsies of the tumour showed no malignancy, laparoscopic subtotal colectomy with lymph node dissection was performed. Histopathological findings revealed localised filiform polyposis with dysplasia. CLINICAL DISCUSSION: Filiform polyposis has been considered a benign inflammatory polyp without any risk of dysplasia. We accumulated previous cases of giant filiform polyposis and reviewed their characteristics. The presented case of filiform polyposis with ulcerative colitis complicated with high-grade dysplasia highlights the importance of considering malignancy in patients with filiform polyposis. CONCLUSION: In cases of giant filiform polyposis, even when no malignancy is detected, surgical resection should be considered for the possibility of a malignant component of dysplasia. Elsevier 2022-09-02 /pmc/articles/PMC9577439/ /pubmed/36268352 http://dx.doi.org/10.1016/j.amsu.2022.104433 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kasuga, So
Anzai, Hiroyuki
Makise, Naohiro
Sonoda, Hirofumi
Nagai, Yuzo
Abe, Shinya
Yokoyama, Yuichiro
Ozawa, Tsuyoshi
Emoto, Shigenobu
Murono, Koji
Sasaki, Kazuhito
Kawai, Kazushige
Nozawa, Hiroaki
Ushiku, Tetsuo
Ishihara, Soichiro
Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title_full Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title_fullStr Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title_full_unstemmed Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title_short Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature
title_sort giant filiform polyposis with high-grade dysplasia: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577439/
https://www.ncbi.nlm.nih.gov/pubmed/36268352
http://dx.doi.org/10.1016/j.amsu.2022.104433
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