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Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation

INTRODUCTION: and Importance: Oral Squamous Cell Carcinoma (OSSC) is one of the most common malignancies of the oral cavity and is one of the ten most prevalent tumours in the world. Control of this tumor is difficult and challenging as its propensity to spread is embedded in the cancer field of epi...

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Autores principales: Adeel, Maira, Andaleeb, Hira, Shakil, Saad, Akhtar, Sareema Eman, Almas, Talal, AlSubai, Abdulla K., AlNajdi, Sara, Alenizi, Aryam Mohammed, Aldhaheri, Khaled Saeed Obaid, Aqil, Shakil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577514/
https://www.ncbi.nlm.nih.gov/pubmed/36268450
http://dx.doi.org/10.1016/j.amsu.2022.104573
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author Adeel, Maira
Andaleeb, Hira
Shakil, Saad
Akhtar, Sareema Eman
Almas, Talal
AlSubai, Abdulla K.
AlNajdi, Sara
Alenizi, Aryam Mohammed
Aldhaheri, Khaled Saeed Obaid
Aqil, Shakil
author_facet Adeel, Maira
Andaleeb, Hira
Shakil, Saad
Akhtar, Sareema Eman
Almas, Talal
AlSubai, Abdulla K.
AlNajdi, Sara
Alenizi, Aryam Mohammed
Aldhaheri, Khaled Saeed Obaid
Aqil, Shakil
author_sort Adeel, Maira
collection PubMed
description INTRODUCTION: and Importance: Oral Squamous Cell Carcinoma (OSSC) is one of the most common malignancies of the oral cavity and is one of the ten most prevalent tumours in the world. Control of this tumor is difficult and challenging as its propensity to spread is embedded in the cancer field of epithelial cells which alter these cells and induce a malignant potential within them. Simultaneous bilateral primary tumours are a rare presentation in the oral cavity which highlights the significance of early diagnosis and treatment. CASE PRESENTATION: Here we present a case of 50-year-old gentleman known case of diabetes, hypertension and chronic history of beetle nut chewing who developed a simultaneously growing bilateral primary OSSC in the buccal mucosa. CT scan revealed a heterogeneous enhancing thickening in the bilateral buccogingival mucosa. A wide local excision of bilateral buccal mucosa with bilateral marginal mandibulectomy with neck dissection was planned. CLINICAL DISCUSSION: The majority of the case report emphasises the relevance of simultaneously developing bilateral primary oral cavity tumours in a patient who had a history of consuming beetle nuts. The independent incidence of bilateral primary OSSC in individuals without a history of tobacco, beetle nut, or alcohol use has also been documented in a small body of research. Due to the considerable clinical variety in its presentation, it is necessary to include bilateral primary OSSC when making a differential diagnosis of OSSC. CONCLUSION: Multiple bilateral primary tumours of the oral cavity are typically on the rise. The prognosis and survival of these individuals are considerably improved by close surveillance and early, expectant management of these cancers. This case study emphasises the value of thorough screening techniques used at an early stage to find these lesions and treat them appropriately.
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spelling pubmed-95775142022-10-19 Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation Adeel, Maira Andaleeb, Hira Shakil, Saad Akhtar, Sareema Eman Almas, Talal AlSubai, Abdulla K. AlNajdi, Sara Alenizi, Aryam Mohammed Aldhaheri, Khaled Saeed Obaid Aqil, Shakil Ann Med Surg (Lond) Case Report INTRODUCTION: and Importance: Oral Squamous Cell Carcinoma (OSSC) is one of the most common malignancies of the oral cavity and is one of the ten most prevalent tumours in the world. Control of this tumor is difficult and challenging as its propensity to spread is embedded in the cancer field of epithelial cells which alter these cells and induce a malignant potential within them. Simultaneous bilateral primary tumours are a rare presentation in the oral cavity which highlights the significance of early diagnosis and treatment. CASE PRESENTATION: Here we present a case of 50-year-old gentleman known case of diabetes, hypertension and chronic history of beetle nut chewing who developed a simultaneously growing bilateral primary OSSC in the buccal mucosa. CT scan revealed a heterogeneous enhancing thickening in the bilateral buccogingival mucosa. A wide local excision of bilateral buccal mucosa with bilateral marginal mandibulectomy with neck dissection was planned. CLINICAL DISCUSSION: The majority of the case report emphasises the relevance of simultaneously developing bilateral primary oral cavity tumours in a patient who had a history of consuming beetle nuts. The independent incidence of bilateral primary OSSC in individuals without a history of tobacco, beetle nut, or alcohol use has also been documented in a small body of research. Due to the considerable clinical variety in its presentation, it is necessary to include bilateral primary OSSC when making a differential diagnosis of OSSC. CONCLUSION: Multiple bilateral primary tumours of the oral cavity are typically on the rise. The prognosis and survival of these individuals are considerably improved by close surveillance and early, expectant management of these cancers. This case study emphasises the value of thorough screening techniques used at an early stage to find these lesions and treat them appropriately. Elsevier 2022-09-08 /pmc/articles/PMC9577514/ /pubmed/36268450 http://dx.doi.org/10.1016/j.amsu.2022.104573 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Adeel, Maira
Andaleeb, Hira
Shakil, Saad
Akhtar, Sareema Eman
Almas, Talal
AlSubai, Abdulla K.
AlNajdi, Sara
Alenizi, Aryam Mohammed
Aldhaheri, Khaled Saeed Obaid
Aqil, Shakil
Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title_full Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title_fullStr Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title_full_unstemmed Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title_short Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation
title_sort bilateral simultaneous primary oral squamous cell carcinoma: a rare presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577514/
https://www.ncbi.nlm.nih.gov/pubmed/36268450
http://dx.doi.org/10.1016/j.amsu.2022.104573
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