Association Between the Cool Temperature-dependent Suppression of Colonic Peristalsis and Transient Receptor Potential Melastatin 8 Activation in Both a Randomized Clinical Trial and an Animal Model

BACKGROUND/AIMS: Several studies have assessed the effect of cool temperature on colonic peristalsis. Transient receptor potential melastatin 8 (TRPM8) is a temperature-sensitive ion channel activated by mild cooling expressed in the colon. We examined the antispasmodic effect of cool temperature on...

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Detalles Bibliográficos
Autores principales: Sugino, Satoshi, Inoue, Ken, Kobayashi, Reo, Hirose, Ryohei, Doi, Toshifumi, Harusato, Akihito, Dohi, Osamu, Yoshida, Naohisa, Uchiyama, Kazuhiko, Ishikawa, Takeshi, Takagi, Tomohisa, Yasuda, Hiroaki, Konishi, Hideyuki, Hirai, Yasuko, Mizushima, Katsura, Naito, Yuji, Tsuji, Toshifumi, Okuda, Takashi, Kagawa, Keizo, Tominaga, Makoto, Itoh, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Neurogastroenterology and Motility 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577569/
https://www.ncbi.nlm.nih.gov/pubmed/36250375
http://dx.doi.org/10.5056/jnm21198

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