MOZ is critical for the development of MOZ/MLL fusion–induced leukemia through regulation of Hoxa9/Meis1 expression

Monocytic leukemia zinc finger protein (MOZ, MYST3, or KAT6A) is a MYST-type acetyltransferase involved in chromosomal translocation in acute myelogenous leukemia (AML) and myelodysplastic syndrome. MOZ is established as essential for hematopoiesis; however, the role of MOZ in AML has not been addre...

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Detalles Bibliográficos
Autores principales: Katsumoto, Takuo, Ogawara, Yoko, Yamagata, Kazutsune, Aikawa, Yukiko, Goitsuka, Ryo, Nakamura, Takuro, Kitabayashi, Issay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577624/
https://www.ncbi.nlm.nih.gov/pubmed/35947126
http://dx.doi.org/10.1182/bloodadvances.2020003490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577624/
https://www.ncbi.nlm.nih.gov/pubmed/35947126
http://dx.doi.org/10.1182/bloodadvances.2020003490

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