Combination of Type I and II tyrosine kinase inhibitors—avapritinib and sunitinib—in refractory gastrointestinal stromal tumor after failure to multi-line therapy: a case report

BACKGROUND: Tyrosine kinase inhibitors (TKIs) are currently the main treatment choice for gastrointestinal stromal tumors (GISTs). However, the long-term use of TKIs can lead to drug resistance. There is no study or clinical report of combination therapies of TKIs that have been approved for marketi...

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Detalles Bibliográficos
Autores principales: Guo, Xiaodan, Huang, Shaoqing, Shi, Yihang, Guan, Zhaoming, Chen, Sile, Feng, Yun, Xia, Yanzhe, Zhang, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577760/
https://www.ncbi.nlm.nih.gov/pubmed/36267752
http://dx.doi.org/10.21037/atm-22-3746

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