Cargando…

Metabolomic markers of glucose regulation after a lifestyle intervention in prediabetes

INTRODUCTION: Disentangling the specific factors that regulate glycemia from prediabetes to normoglycemia could improve type 2 diabetes prevention strategies. Metabolomics provides substantial insights into the biological understanding of environmental factors such as diet. This study aimed to ident...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sevilla-Gonzalez, Magdalena del Rocio, Manning, Alisa K, Westerman, Kenneth E, Aguilar-Salinas, Carlos Alberto, Deik, Amy, Clish, Clary B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577902/ https://www.ncbi.nlm.nih.gov/pubmed/36253014 http://dx.doi.org/10.1136/bmjdrc-2022-003010

Ejemplares similares

Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans
por: Chen, Zsu-Zsu, et al.
Publicado: (2022)

Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program
por: Walford, Geoffrey A., et al.
Publicado: (2016)

Dimethylglycine Deficiency and the Development of Diabetes
por: Magnusson, Martin, et al.
Publicado: (2015)

Changing Metabolic Signatures of Amino Acids and Lipids During the Prediabetic Period in a Pig Model With Impaired Incretin Function and Reduced β-Cell Mass
por: Renner, Simone, et al.
Publicado: (2012)

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
por: Scott, Robert A., et al.
Publicado: (2012)

Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition(1)(2)(3)
por: Di Giovanni, Valeria, et al.
Publicado: (2016)

Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent
por: Haslam, Danielle E, et al.
Publicado: (2021)

Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
por: Powe, Camille E., et al.
Publicado: (2021)

Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium
por: Palmer, Nicholette D., et al.
Publicado: (2015)

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
por: Floegel, Anna, et al.
Publicado: (2013)

Metabolomics-based multidimensional network biomarkers for diabetic retinopathy identification in patients with type 2 diabetes mellitus
por: Zuo, Jingjing, et al.
Publicado: (2021)

Human serum metabolomic analysis reveals progression for high blood pressure in type 2 diabetes mellitus
por: Zhang, Yin, et al.
Publicado: (2021)

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations
por: Chen, Brian H., et al.
Publicado: (2016)

Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials
por: Papandonatos, George D., et al.
Publicado: (2015)

Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study
por: Li, Qian, et al.
Publicado: (2020)

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
por: Srinivasan, Shylaja, et al.
Publicado: (2021)

Placental Adiponectin Gene DNA Methylation Levels Are Associated With Mothers’ Blood Glucose Concentration
por: Bouchard, Luigi, et al.
Publicado: (2012)

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth
por: Scholtens, Denise M., et al.
Publicado: (2016)

Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
por: Hwang, Joo-Yeon, et al.
Publicado: (2015)

A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts
por: Nogal, Ana, et al.
Publicado: (2023)

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study
por: Hidalgo, Bertha, et al.
Publicado: (2014)

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region
por: Bowker, Nicholas, et al.
Publicado: (2021)

CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand
por: Russell, Emily M, et al.
Publicado: (2022)

Contribution of Common Genetic Variation to the Risk of Type 2 Diabetes in the Mexican Mestizo Population
por: Gamboa-Meléndez, Marco Alberto, et al.
Publicado: (2012)

hZnT8 (Slc30a8) Transgenic Mice That Overexpress the R325W Polymorph Have Reduced Islet Zn(2+) and Proinsulin Levels, Increased Glucose Tolerance After a High-Fat Diet, and Altered Levels of Pancreatic Zinc Binding Proteins
por: Li, Li, et al.
Publicado: (2017)

Grg3/TLE3 and Grg1/TLE1 Induce Monohormonal Pancreatic β-Cells While Repressing α-Cell Functions
por: Metzger, David E., et al.
Publicado: (2014)

Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study
por: Yuan, Shuai, et al.
Publicado: (2020)

Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays
por: Bian, Xiaofang, et al.
Publicado: (2016)

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes
por: Mercader, Josep M., et al.
Publicado: (2017)

A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes
por: Ferreira, Ricardo C., et al.
Publicado: (2014)

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
por: Keildson, Sarah, et al.
Publicado: (2014)

Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men
por: Pimentel, Grégory, et al.
Publicado: (2018)

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children(1)(2)(3)
por: Lee, Sun Eun, et al.
Publicado: (2017)

Identification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System–Related Oligosaccharides
por: Pimentel, Grégory, et al.
Publicado: (2020)

Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish
por: Axton, Elizabeth R, et al.
Publicado: (2019)

Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome
por: Zhu, Jing, et al.
Publicado: (2021)

Urine Metabolite Profiles and Nutrient Intake Based on 4-Day Weighed Food Diary in Habitual Vegans, Vegetarians, and Omnivores
por: Lindqvist, Helen M, et al.
Publicado: (2020)

DHA Supplementation Attenuates Inflammation-Associated Gene Expression in the Mammary Gland of Lactating Mothers Who Deliver Preterm
por: Adams, Joselyn M, et al.
Publicado: (2022)

Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
por: Karabegović, Irma, et al.
Publicado: (2022)

Consistent Directions of Effect for Established Type 2 Diabetes Risk Variants Across Populations: The Population Architecture using Genomics and Epidemiology (PAGE) Consortium
por: Haiman, Christopher A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qdk4umen5bfbtgqb4tlj4e3li5