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Localized ablative immunotherapy drives de novo CD8(+) T-cell responses to poorly immunogenic tumors
BACKGROUND: Localized ablative immunotherapies hold great promise in stimulating antitumor immunity to treat metastatic and poorly immunogenic tumors. Tumor ablation is well known to release tumor antigens and danger-associated molecular patterns to stimulate T-cell immunity, but its immune stimulat...
Autores principales: | Hoover, Ashley R, Kaabinejadian, Saghar, Krawic, Jason R, Sun, Xiao-Hong, Naqash, Abdul Rafeh, Yin, Qian, Yang, Xinbo, Christopher Garcia, K, Davis, Mark M, Hildebrand, William H, Chen, Wei R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577935/ https://www.ncbi.nlm.nih.gov/pubmed/36253002 http://dx.doi.org/10.1136/jitc-2022-004973 |
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