IgD (+) age‐associated B cells are the progenitors of the main T‐independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

Age‐associated B cells (ABC) accumulate with age and are associated with autoimmunity and chronic infection. However, their contributions to acute infection in the aged and their developmental pathways are unclear. We find that the response against influenza A virus infection in aged mice is dominat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kugler‐Umana, Olivia, Zhang, Wenliang, Kuang, Yi, Liang, Jialing, Castonguay, Catherine H., Tonkonogy, Susan L., Marshak‐Rothstein, Ann, Devarajan, Priyadharshini, Swain, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577953/
https://www.ncbi.nlm.nih.gov/pubmed/36056604
http://dx.doi.org/10.1111/acel.13705

Ejemplares similares

Ejemplares similares