Conserved age‐related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories

In humans, associative memories are more susceptible to age‐related cognitive decline (ARCD) than are recognition memories. Reduced cAMP/cGMP signaling in the hippocampus may contribute to ARCD. Here, we found that both aging and traumatic brain injury‐associated dementia increased the expression of...

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Detalles Bibliográficos
Autores principales: Pilarzyk, Katy, Porcher, Latarsha, Capell, William R., Burbano, Steven D., Davis, Jeff, Fisher, Janet L., Gorny, Nicole, Petrolle, Siena, Kelly, Michy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577960/
https://www.ncbi.nlm.nih.gov/pubmed/36073342
http://dx.doi.org/10.1111/acel.13687

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