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Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report

INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTA...

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Detalles Bibliográficos
Autores principales: Chamlagain, Rajan, Shah, Sangam, Thapa, Sangharsha, Basnet, Madan, kandel, Bipin, Paudel, Basanta Sharma, Dhital, Roman, Pokhrel, Apil, Khanal, Pitambar, Paudel, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577962/
https://www.ncbi.nlm.nih.gov/pubmed/36268402
http://dx.doi.org/10.1016/j.amsu.2022.104790
Descripción
Sumario:INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTATION: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies. DISCUSSION: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required. CONCLUSION: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary.