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Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report

INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTA...

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Autores principales: Chamlagain, Rajan, Shah, Sangam, Thapa, Sangharsha, Basnet, Madan, kandel, Bipin, Paudel, Basanta Sharma, Dhital, Roman, Pokhrel, Apil, Khanal, Pitambar, Paudel, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577962/
https://www.ncbi.nlm.nih.gov/pubmed/36268402
http://dx.doi.org/10.1016/j.amsu.2022.104790
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author Chamlagain, Rajan
Shah, Sangam
Thapa, Sangharsha
Basnet, Madan
kandel, Bipin
Paudel, Basanta Sharma
Dhital, Roman
Pokhrel, Apil
Khanal, Pitambar
Paudel, Sandip
author_facet Chamlagain, Rajan
Shah, Sangam
Thapa, Sangharsha
Basnet, Madan
kandel, Bipin
Paudel, Basanta Sharma
Dhital, Roman
Pokhrel, Apil
Khanal, Pitambar
Paudel, Sandip
author_sort Chamlagain, Rajan
collection PubMed
description INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTATION: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies. DISCUSSION: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required. CONCLUSION: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary.
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spelling pubmed-95779622022-10-19 Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report Chamlagain, Rajan Shah, Sangam Thapa, Sangharsha Basnet, Madan kandel, Bipin Paudel, Basanta Sharma Dhital, Roman Pokhrel, Apil Khanal, Pitambar Paudel, Sandip Ann Med Surg (Lond) Case Report INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTATION: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies. DISCUSSION: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required. CONCLUSION: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary. Elsevier 2022-09-28 /pmc/articles/PMC9577962/ /pubmed/36268402 http://dx.doi.org/10.1016/j.amsu.2022.104790 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Chamlagain, Rajan
Shah, Sangam
Thapa, Sangharsha
Basnet, Madan
kandel, Bipin
Paudel, Basanta Sharma
Dhital, Roman
Pokhrel, Apil
Khanal, Pitambar
Paudel, Sandip
Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title_full Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title_fullStr Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title_full_unstemmed Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title_short Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
title_sort teenager with acute psychosis due to non-paraneoplastic anti-n-methyl-d-aspartate receptor encephalitis with a successful recovery: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577962/
https://www.ncbi.nlm.nih.gov/pubmed/36268402
http://dx.doi.org/10.1016/j.amsu.2022.104790
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