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Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report
INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTA...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577962/ https://www.ncbi.nlm.nih.gov/pubmed/36268402 http://dx.doi.org/10.1016/j.amsu.2022.104790 |
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author | Chamlagain, Rajan Shah, Sangam Thapa, Sangharsha Basnet, Madan kandel, Bipin Paudel, Basanta Sharma Dhital, Roman Pokhrel, Apil Khanal, Pitambar Paudel, Sandip |
author_facet | Chamlagain, Rajan Shah, Sangam Thapa, Sangharsha Basnet, Madan kandel, Bipin Paudel, Basanta Sharma Dhital, Roman Pokhrel, Apil Khanal, Pitambar Paudel, Sandip |
author_sort | Chamlagain, Rajan |
collection | PubMed |
description | INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTATION: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies. DISCUSSION: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required. CONCLUSION: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary. |
format | Online Article Text |
id | pubmed-9577962 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-95779622022-10-19 Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report Chamlagain, Rajan Shah, Sangam Thapa, Sangharsha Basnet, Madan kandel, Bipin Paudel, Basanta Sharma Dhital, Roman Pokhrel, Apil Khanal, Pitambar Paudel, Sandip Ann Med Surg (Lond) Case Report INTRODUCTION: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation. CASE PRESENTATION: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies. DISCUSSION: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required. CONCLUSION: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary. Elsevier 2022-09-28 /pmc/articles/PMC9577962/ /pubmed/36268402 http://dx.doi.org/10.1016/j.amsu.2022.104790 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Chamlagain, Rajan Shah, Sangam Thapa, Sangharsha Basnet, Madan kandel, Bipin Paudel, Basanta Sharma Dhital, Roman Pokhrel, Apil Khanal, Pitambar Paudel, Sandip Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title | Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title_full | Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title_fullStr | Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title_full_unstemmed | Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title_short | Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report |
title_sort | teenager with acute psychosis due to non-paraneoplastic anti-n-methyl-d-aspartate receptor encephalitis with a successful recovery: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577962/ https://www.ncbi.nlm.nih.gov/pubmed/36268402 http://dx.doi.org/10.1016/j.amsu.2022.104790 |
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