Loss of the fructose transporter SLC2A5 inhibits cancer cell migration

Metastasis is the primary cause of cancer patient death and the elevation of SLC2A5 gene expression is often observed in metastatic cancer cells. Here we evaluated the importance of SLC2A5 in cancer cell motility by silencing its gene. We discovered that CRISPR/Cas9-mediated inactivation of the SLC2...

Descripción completa

Detalles Bibliográficos
Autores principales: Groenendyk, Jody, Stoletov, Konstantin, Paskevicius, Tautvydas, Li, Wenjuan, Dai, Ning, Pujol, Myriam, Busaan, Erin, Ng, Hoi Hei, Boukouris, Aristeidis E., Saleme, Bruno, Haromy, Alois, Cui, Kaisa, Hu, Miao, Yan, Yanan, Zhang, Rui, Michelakis, Evangelos, Chen, Xing-Zhen, Lewis, John D., Tang, Jingfeng, Agellon, Luis B., Michalak, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578049/
https://www.ncbi.nlm.nih.gov/pubmed/36268513
http://dx.doi.org/10.3389/fcell.2022.896297

Ejemplares similares

Ejemplares similares