Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation

[Image: see text] Targeted protein degradation (TPD) is a promising therapeutic modality to modulate protein levels and its application promises to reduce the “undruggable” proteome. Among TPD strategies, Proteolysis TArgeting Chimera (PROTAC) technology has shown a tremendous potential with attract...

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Detalles Bibliográficos
Autores principales: Ruffilli, Camilla, Roth, Sascha, Rodrigo, Monica, Boyd, Helen, Zelcer, Noam, Moreau, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578132/
https://www.ncbi.nlm.nih.gov/pubmed/36268122
http://dx.doi.org/10.1021/acsptsci.2c00142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578132/
https://www.ncbi.nlm.nih.gov/pubmed/36268122
http://dx.doi.org/10.1021/acsptsci.2c00142

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